Structure-activity relationships in aspartic peptidases - biochemical and structural characterization of selected conserved sequence elements in retropepsins.

Abstrakt

Structure-activity relationships in retroviral proteinases, mutational analysis, physical and kinetic characterisation.

Klíčová slova

• Konvalinka
• Jan
• 220183218 aspartic peptidases
• HIV protease
• firemen's grip
• structure-activity relationship
• viral resistance
• protease inhibitors