2-Anisidine is a genotoxic carcinogen: evidence for 2-anisidine-DNA adduct formation in vitro a in vivo

Abstrakt

These reports, the first report on the metablism of 2-anisidine by human enzymes, strongly suggest a carcinogenic potency of this rodent carcinogen for humans.

Klíčová slova

• Stiborová
• Marie 221951285 2-anisidine
• genotoxic carcinogen
• DNA adduct
• metabolic activation