The first identification of Sudan I [1-phenylazo-2-hydroxynaphthalene] as a potential carcinogen for human

Abstract

Report on Sudan I metabolism in human microsomes by CYP1A1 and CYP 3A4, strongly suggesting a carcinogenic potency of this rodent carcinogen for human.

Keywords

• Marie Stiborová
• tel.: [phone] Sudan 1
• human cytochromes P450
• CYP1A1
• CYP3A4
• carcinogenity