Naftoflavone as a model ligand of the active site of CYP3A

Abstract

Naftoflavone as a compound binding the active site of CYP3A in different ways: as its inhibitor and stimulator, depending on the substrate type.

Keywords

• Hodek
• l. 1285 Cytochrome P450
• CYP3A
• naphthoflavone
• coopretivity
• metabolism