Metabolism of -naphthoflavone and its thio-analogue by microsomal system

Abstrakt

-Naphthoflavone and its thio-analogue is metabolized by microsomal system was examined. Thio-analogue of naphthoflavone is metabolized via conversion to naphthoflavone.

Klíčová slova

• Hodek
• l. 1285 Cytochrome P450
• CYP3A4
• flavonoids
• metabolism
• HPLC
• mass spectrometry