Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase

Abstrakt

Carcinogenic aristolochic acid activated by human NQO1 forms the same DNA adducts foun in patients with Chines herbs nephropathy

Klíčová slova

• Stiborová
• Marie 221951285 Chinese herbs nephropathy
• aristolochic acid
• human cytosolic enzymes
• NAD(P)H:quinone oxidoreductase