Abstrakt
The advanced stage of prostate cancer called castration resistant prostate cancer (CRPC) is an incurable disease with median survival around 15 month. More than 85% of patients suffering from CRPC exhibit metastases, mostly in bone.
Due to the ongoing metastatic process we are able to detect circulating tumor cells (CTCs) in the blood of the majority of the patients with CRPC. We aimad at the detection of CTCs in the blood of patients with CRPC together with their characterization a study of their behavior during in vitro cultivation.