Rat cytochromes P450 are suitable model enzymes mimicking the metabolic activation of anticancer drug ellipticine in humans

Abstrakt

Rats are more suitable models than rabbits mimicking the metabolic activation of ellipticine in humans.

Klíčová slova

• Stiborová
• Marie 221951285 ellipticine
• cytochrome P450
• metabolic activation
• anticancer drug