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Inhibition of interleukins 12 and 23 - experience of plaque psoriasis therapy by ustekinumab

Publication at First Faculty of Medicine, Faculty of Medicine in Hradec Králové |
2013

Abstract

Ustekinumab is a fully human monoclonal antibody that binds to the p40 protein which is a subunit of IL-12 and IL-23rd According to data from clinical trials and clinical practice experience is a very effective treatment for moderate to severe plaque psoriasis with a good safety profile and excellent compliance.