Abstract
Patient adherence to recommended treatment varies. The number of actually used doses of the drug over a recommendation mainly affect the number of tablets prescribed, frequency of use, age, duration of treatment and side effects of therapy.
Type 2 diabetes mellitus type is the typical model situation in which the patient adherence to therapy is reduced. Non-adherence increases the number of hospitalizations, mortality, and very likely economic costs in the treatment of type 2 diabetes type.
Antidiabetic drugs in fixed combinations increase adherence to therapy and improved glycemic control. One of the ideal combination is complementary in terms of the effect of metformin and gliptins.
Fixed dose combination oral antidiabetic agents are, despite certain limitations, effective extension options pharmacological therapy of type 2 diabetes type.