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Haemophilia – a contemporary overview

Publication at Second Faculty of Medicine |
2013

Abstract

Haemophilia A and B are the most common congenital of blood coagulation disorders that a physician can come across in his practice. Thanks to advances in medicine, haemophilia is now a fully treatable condition and haemophiliacs can have life expectancy fully comparable to the general population.

The prognosis for haemophiliac patients was greatly improved by introducing at-home treatment and prophylactic treatment and by development of new coagulation factor replacement preparations. The care for haemophiliacs in Czech Republic was greatly improved by the organisational and expert-level measures realised as a part of the Czech National Haemophilia Programme and by centralisation of haemophiliac care into larger centres which have sufficient experience with treatment of such patients.

A hope for the future is seen in factor replacement preparations with prolonged duration of effect and in gene therapy.