Evaluation of WT1 expression in bone marrow vs peripheral blood samples of children with acute myeloid leukemia-impact on minimal residual disease detection

Abstrakt

Wilms' tumor gene 1 (WT1) is located on chromosome 11p13. As a zinc finger transcription factor, WT1 regulates expression of many target genes involved in regulation of cell cycle, proliferation, differentiation and apoptosis.

Klíčová slova

• gene-expression
• time
• quantification
• prediction
• aml