Publication at Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine |
2013
Abstract
We report a case of mycotic pneumonia in a patient with acute myeloblastic leukemia. Rhizopus microsporus was identified as an agent of mucormycosis and proven by microscopy and culture.
The determination of the isolates was supported by molecular methods. Combined treatment with surgery (right-sided pneumonectomy) and systemic amphotericin B and posaconazole antifugal therapy was chosen.
In this case, amphotericin B NeoSensitabs tablets gave false "resistant" results on Mueller-Hinton agar when using the disk diffusion test. There was a good correlation between the Etest (16 h) and Sensititre YeastOne microplate (24 h) for amphotericin B.