Abstract
Therapy of autochthonous parasitic infections Antiparasitic drugs represent a heterogeneous group of both natural and synthetic organic and anorganic substances. Most of them have narrow spectrum of effect which is caused by differences in metabolism and cell structure in different groups of parasites.
For most parasitic infections, there still exist only a limited number of drugs available for their treatment. Highly toxic drugs synthesized many decades ago are still in use.
The exact mechanism of action was described only in a few groups of antiparasitic drugs, for example in 5-nitroimidazoles against anaerobic protozoa and benzimidazoles against parasitic nematodes. Overview of the current therapy of the common autochthonous parasitic infections and characteristics of common antiparasitic drugs are presented in this review article.