Human cytochrome P450 1A1 is responsible for metabolic activation and detoxication of carcinogenic azo dye Sudan I (1-phenylazo-2-hydroxynaphthalene, Solvent Yellow 14)

Abstract

Human cytochrome P450 1A1 is responsible for metabolic activation and detoxication of carcinogenic azo dye Sudan I

Keywords

• 1-(Phenylazo)-2-naphthol
• azo compounds
• risk assessment
• metabolism
• cytochromes P450