Iron-induced changes in pyruvate metabolism of Tritrichomonas foetus and involvement of iron in expression of hydrogenosomal proteins

Abstract

Reversible metabolic switch from the hydrogenosomal to cytosolic pyruvate metabolism was induced by iron depletion in Tritrichomonas foetus. The results demonstrated the iron-dependent control of the expression of hydrogenosomal proteins operati

Keywords

• Tritrichomonas foetus
• anaerobic protist
• iron
• pyruvate metabolism
• hydrogenosome
• ferredoxin
• pyruvate:ferredoxin oxidoreductase
• hydrogenase
• pyruvate decarboxylase
• transcription