Interaction of anticancer drug ellipticine with cytochrome P450

Abstrakt

Ellipticine is alkaloids exhibiting significant antineoplastic and anti-HIV activities. The multiple effects of ellipticine on CYPs were studied in details.

Klíčová slova

• CST//cytochrome P450
• ellipticine
• interactiction with CYP
• inhibition of specific CYP activities