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Proteases and antiproteases in health and disease - a review V. Metallopeptidases and their inhibitors

Publication at Faculty of Medicine in Pilsen |


The metallopptidases are allocated into 8 clans, of which matrix metalloproteinases (MMP) play important role in human physiology and pathology. The action of activated MMPs is blocked by alpha-2-macroglobulin and tissue inhibitors of MMPs.