Ellipticine forms covalent DNA adducts in rats with properties similar to adducts formed in vitro after its activation by cytochromes P450 or peroxidases

Abstract

Ellipticine forms covalent DNA adducts in rats with properties similar to adducts formed in vitro after its activation by cytochromes P450 or peroxidases

Keywords

• ellipticine
• cytochrome P450
• DNA adducts
• metabolism
• peroxidase