Role of the leukemia-inhibitory factor gene mutations in infertile women: The embryo-endometrial cytokine cross talk during implantation - a delicate homeostatic equilibrium

Abstrakt

The leukemia inhibitory factor (LIF) plays essential role in the preimplantation embryo development and the blastocyst implantation. The LIF gene mutations in women contribute to the implantation failure and subsequent infertility.