Isolation of rat hepatic D,T-diaphorase and study of its interaction with carcinogenic aristolochic acids

Abstrakt

D,T-diaphorase is a flavoprotein which catalyzes the two-electron reduction of xenobiotic quinones. D,T-diaphorase possesses nitroreductase activity for a naturally occurring nephrotoxic and carcinogenic nitrofenanthrene derivative, aristolochic

Klíčová slova

• CST//Aristolochic acids
• D
• T-diaphorase
• carcinogens
• nephrotoxicity