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Detection of carcinoma by means of endoscopic cytoscopy in the area of ulcerative colitis

Publication at Central Library of Charles University, Faculty of Medicine in Pilsen |
2008

Abstract

Endoscopic cytoscopy (ECS) is a recently developed method of contact endoscopy. ECS enables us to observe the mucosal surface of the area under examination with regard to the architecture as well as cytologic details such as the nucleus, nucleolus and cell membranes.

In clinical practice, ECS can be of great value as it can be used directly during a routine endoscopic examination and thus the highly magnified morphological image can be viewed simultaneously with endoscopy. It is thus possible to distinguish inflammatory and neoplastic changes by means of the ECS probe examining details of the mucosa.

It is obvious that the results obtained so far have to be compared with those of conventional histological examination of biopsy specimens in order to confirm the diagnostic and histopathologic precision of ECS. A 48-year-old man with a 12-year history of ulcerative colitis (UC) complained of seasonal relapses.

The patient had a pancolitis disease, and the whole colon was examined endoscopically during a follow-up examination.