Renal haemodynamic, microcirculatory, metabolic and histopathologic responses to peritonitis-induced septic shock in pigs

Abstract

A fundamental step is the use of animal models designed to meet the criteria of human sepsis. Therefore, we dynamically assessed renal haemodynamic, microvascular and metabolic responses to, and ultrastructural sequelae of, sepsis in a porcine model of fecal peritonitis-induced progressive hyperdynamic sepsis.