IgE-Mediated Sensitization to Malassezia in Atopic Dermatitis: More Common in Male Patients and in Head and Neck Type
2014
Abstrakt
Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Malassezia, the predominant skin microbiota fungus, is considered to exacerbate AD, especially in a subset of patients with head and neck type AD (HNAD).
In the present study, the relationship between AD and sensitization to Malassezia antigens was investigated. We assessed 173 patients with AD.
The severity of eczema was determined with Eczema Area and Severity Index (EASI); the type of AD, namely, head and neck type, was reported as well. The total serum IgE and specific IgE to Malassezia were determined and correlated with clinical picture of AD, sex, age, and the EASI.