Glycogen phosphorylase BB levels are associated with haemodynamic parameters in cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt insertion

Abstract

Transjugular intrahepatic portosystemic shunts (TIPS) have become a widely accepted tool in the treatment of patients with symptomatic portal hypertension. The aim of our study was to assess glycogen phosphorylase BB (GPBB) concentration in relation to echocardiographic and haemodynamic parameters in patients before and after TIPS insertion.

GPBB concentration after TIPS significantly correlated with baseline systemic vascular resistence and cardiac index. GPBB concentration measurement may be a useful tool for monitoring myocardial ischemia during a TIPS procedure.

Keywords

• glycogen phosphorylase BB
• cardiac marker
• cirrhosis
• biochip
• portal hypertension
• TIPS