Solid Phase Synthesis of Glycopeptide Dendrimers with Tn Antigenic Structure and their Biological Activities. Part I

Abstract

Multiple antigenic prptides containing dimeric Tn antigen has been prepared. This conjugate can be used for immunological studies and for preparation of anti-tumour vaccine event. for purification of anti-Tn antibodies.

Keywords

• solid phase peptide synthesis (SPPS)
• glycopeptide dendrimers
• multiple antigen glycopeptide systems (MAGs)
• Tn antigens
• tumour associated antigens
• molecular modelling