Abstract
The aim of out study is to assess early and long-term outcomes of endovascular treatment of deep venous thrombosis. 92 patients (62 males, 30 females, average age 27,2 years) with deep venous thrombosis were treated with local fibrinolysis. Alteplase (a recombinant tissue plasminogen activator) was used as fibrinolytic agent.
We used also other endovascular techniques (balloon angioplasty, stent implantation, mechanical thrombolysis) in the majority of patients. Initial technical success was achieved in 82 out of 92 patients (90 %), 96,5 % in acute, 40 % in chronic thromboses, 88 % in pelvic, 91 % in femoral and 100 % in subclavial veins.
Overall passability in 12 months was 86 %, 85 % in pelvic, 90 % in femoral and 78,5 % in subclavial veins. Twelve months later, 90,7 % of patients were completely free from any clinical signs of postthrombotic syndrome.
Serious bleeding with the need of blood transfusion occurred in 3,3 % of patients. Haematoma in the location of puncture was in 14 % of patients.
No death, clinical signs of pulmonary embolism or intracranial haemorrhage occurred. Our outcomes validate, that this kind of deep venous thrombosis treatment is safe and efficient method and its decreases an incidence of postthrombotic syndrome.