Publication at Faculty of Science |
2009
Abstract
Saccharomyces cerevisiae colony transition between major developmental phases is accompanied by striking transcription changes; the development within particular phase is guided mostly at the post-transcriptional level. Cells located at the colony margin export higher amounts of ammonium than central cells and activate an adaptive metabolism.
Central chronologically aged cells are unable to undergo these changes but they maintain higher levels of various stress-defence enzymes. These divergent properties of both cell types determine their consequent dissimilar fate.