Publikace na Přírodovědecká fakulta |
2008
Abstrakt
The reactions of selected triterpenic oxo compounds with Lawesson's reagent were investigated. We examined sulfurization of some oxygen compounds and for these reactions several hindered ketones, one aldehyde, α-hydroxyketones, esters, or anhydrides were chosen.
We synthesized 15 new sulfur derivatives, including thioketone 16, dimeric sulfides 17-19, and thiaderivatives 20-22. We also observed unusual transformations, which afforded oxathiaphosphinines 23a, 23b, and dithiaphospholanes 24.
The prepared compounds failed to demonstrate any significant cytotoxic activit