A Novel Protein Acts as a Negative Regulator of Prophenoloxidase Activation and Melanization in the Freshwater Crayfish Pacifastacus leniusculus

Abstract

Paper describes a novel mechanisms of immune system of invertebrates. The crucial influence of melanization reaction for invertebrate immune system is further supported by a discovery of negative regulator of this reaction in crayfish.

Keywords

• innate immunity
• phenoloxidase
• defense
• trypsinogen
• inhibitor
• component
• cloning
• system