RAD51 135G -> C modifies breast cancer risk among BRCA2 mutation carriers: Results from a combined analysis of 19 studies

Abstrakt

Rare homozygous SNP in UTR of RAD51 gene (CC) 135G>C increses risk of breast cancer development in BRCA2 mutation carriers HR=3.18 (95% CI 1.39-7.27; p= 0.0007)