Mechanisms of the inhibition of endplate acetylcholine receptors by antiseptic chlorhexidine (experiments and models)

Abstract

Given the very widespread use of antiseptics chlorhexidine in surgery, infant and communal hygiene, the publication of the findings irreversibilní inhibition of neuromuscular disc model and explanation of its action to be taken into account when assessing the side-effects in the normal application of chlorhexidine, and an explanation of fatal cases after an inadvertent overdosage and systemic administration

Keywords

• Acetylcholine
• endplate currents