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The question waiting to be asked: Innate immunity receptors in the perspective of zoological research.

Publication at Faculty of Science |
2009

Abstract

This review paper suggests the importance of evolutionary and ecological research of the structure and polymorphism of innate immunity receptors in wild living animals. Giving the example of Toll-like receptors and their polymorphism in humans and domestic animals it points out the importance of variability in these receptors for resistance to various diseases.

So far we have no information about the polymorphism of the genes for these receptors in free-living animals. Thus also the evolutionary and ecological aspects of the polymorphism still wait to be studied.