Abstract
Subarachnoid hemorrhage (SAH) is a serious, life-threatening cause of morbidity and mortality in the world. Despite the progression in imaging and laboratory methods remain a significant percentage of patients with SAH misdiagnosed.
Unenhanced CT of the brain is the investigation of choice for establishing presence of SAH. Cerebrospinal fluid (CSF) spectrophotometry is recommended in CT negative patients, when clinical suspicion remains high.
The specimen for spectrophotometry has certain requirements for the collection, handling and transport to the laboratory, however, can be a valuable diagnostic tool. According to recent recommendations is appropriate to interpret the result using serum protein, serum bilirubin and CSF protein levels.
In addition to CSF spectrophotometric examination other laboratory tests as CSF cytology, red cell count examination or CSF ferritin levels can be useful.