Chimerism-directed adoptive immunotherapy in the prevention and treatment of post-transplant relapse of leukemia in childhood

Abstract

We present the role of frequent monitoring of hematopoietic chimerism in the prediction of posttransplantrelapse and our initial experience with adoptive immunotherapy in the prevention and treatment of hematologicrelapse in children after allogeneic hematopoietic stem celltransplantation.

Keywords

• leukemia
• post-transplant relapse
• hematopoietic chimerism
• adoptive immunotherapy