Immunohistochemical Methods in the Differential Diagnosis of Primary Traumatic and Subsequent Secondary Cerebral Changes

Abstract

The combination of the immunohistochemical examinations seemed a suitable method for differentiating primary cerebral injury (diffuse axonal injury and minor contusion foci in the corpus callosum and the margin of the pons) from secondary changes (haemorrhages in the median portion of the pons which developed shortly before death as a manifestation of haemodynamic disorders associated with cerebral oedema).