Abstract
There is strong evidence suggesting that HPV infection with high risk virus subtypes is an important etiological factor in the cervical neoplasia pathogenesis. Our study group consist of 152 patients that underwent cone biopsy of the cervix based on histopathological findings of high grade SIL Six month following the treatment we performed HPV/HR test, expert colposcopy and conventional cytology.
From our study we concluded that there is high percentage (51 [35,6%]) of HPV positivity persistence or/and reinfection in treated women. In the follow up of the study group we found 5 cases of HG SIL and relatively higher incidence of the abnormalities in the cytology smear.
In the group of 92 HPV negative patients there was no manifestations of high grade SIL finding in 18 month follow up.