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Invasive and Non-invasive Methods in the Differential Diagnosis of Uncontrollable Epilepsies

Publication at Second Faculty of Medicine, Third Faculty of Medicine |
1998

Abstract

The basis of the differential diagnosis of uncontrollable epilepsies are above all non-invasive imaging methods and long-term video-EEG monitoring. In patients included in an epileptosurgical programme also semi-invasive and invasive methods play a role to a different extent.

The objective of the examination is to obtain a maximum of valid information while reducing the burdening of the patient and financial costs to a minimum. Therefore a suitable combination of different methods and ways of evaluation of their effectiveness are sought.

One of the criteria of usefulness of an applied method in operated patients can be a correlation with the postoperative frequency of attacks. In the submitted trial the authors evaluated the yield of video-KEG monitoring in 94 patients who were examined on account of uncontrollable epilepsy at the Unit for intensive monitoring at the Faculty Hospital Motel in 1995-1997.

In all patients magnetic resonance (MRI) was applied; among preoperative methods also proton magnetic resonance spectroscopy (1RMRS) was included. In operated patients the authors compared preoperative findings and applied methods with postoperative results.

A favourable postoperative course confirmed the correct indication in 65% of patients, the best results were obtained in patients with temporal epilepsy (76% successfully operated). In patients operated only on the basis of non-invasive methods the postoperative development was favourable in 81%, in invasively monitored patients surgery was successful in half of the patients.