Contemporary status and perspectives of fluoroquinolones from the clinical and microbiological aspect
Abstract
The author presents a review on the contemporary position of fluoroquinolones from the microbiological and clinical aspect. He submits basic data on the mechanism of action of these drugs and development of resistance displayed by infectious agents.
Favourable pharmacokinetics make wide clinical use of these drugs possible. Indicriminate administration could debase these drugs possible.
Indiscriminate administration could debase these very valuable antimicrobial drugs. This is why the author presents in his paper the main clinical indications for their therapeutic use.
To complete the problem the author makes suggestions of suitable combinations and draws attention to possible therapeutic interactions and undesirable effects, incl. contraindications.