Abstract
In 1988 - 1994 at the Paediatric Surgical Clinic,Faculty Hospital Motol splenectomy was performed in 66 children. Indication for splenectomy were haematological diseases (52), malignant and benign tumours (12) and congestive splenomegaly associated with cytopenia (2).
The group does not comprise patients operated on account of injury. The most frequent haematological indications for splenectomy include haemolytic anaemia, chronic idiopathic thrombocytopenic purpura, hypersplenism and other conditions (haematological malignities).
The investigation is focused on haematological indications of splenectomy in childhood and its effect on treatment of the basic disease. Splenectomy on account of hereditary spherocytosis was performed in 31 patients.
In all after surgery normalization of the haemogram was recorded. Of 11 patients, who were operated on account of idiopathic surgery normalization of the haemogram was recorded, ut il patients, who were operated on account of idiopathic observed.
In two patients the rise of thrombocytes was slight however haemorrhagic manifestations of the disease receded. One patient operated on account of thrombocytopenia linked to the X chromosome died.
In nine patients operated on account of other haematological indications after splenectomy improved values of the haemogram were observed. The immune state of the patients was not investigated.