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Experimental Pharmacotherapy of Sensitization to Opioids

Publication at Third Faculty of Medicine |
2001

Abstract

This article presents a review of findings made until now within the experimental treatment of sensitisation mainly on locomotion stimulating effects of opioids in mice and rats and potential neurobiological mechanism of its generation. Most studies focus on the dopaminergic, glutamatergic, gabaergic and serotoninergic receptor systems.