Antidepressants in the Treatment of Depresive Disorder during Pregnancy and After Delivery

Abstract

The author reviews results of clinical trials of tricyclic antidepressants, selective serotonin reuptake inhibitors and so called 'newer antidepressants' used during pregnancy; presents main risks of their use during this period and after delivery /teratogenicity, perinatal toxicity, behavioural teratogenicity etc./. Risks for nursing infants are also resumed.

The basic principles of pharmacological treatment of depression during pregnancy and breastfeeding /patient's information, choice of treatment, choice of antidepressant, dosage of antidepressant, and prevention of postpartum depression/ are discussed.

Keywords

• Antidepressants
• Treatment
• Depresive
• Disorder
• during
• Pregnancy
• After
• Delivery