Abstract
Voxel based morphometry (VBM) is a fully automated objective method for processing MRI images. The paper outlines the main principles, advantages and disadvantages of this technique over classical morphometric analyses based on semimanual measurement of regions of interest.
Despite the increasing popularity of VBM, there are only few papers looking at limitations and quality of this technique. In the second part of the paper we present the synopsis of our study looking at test retest reliability of VBM.