Effect of repetitive transcranial magnetic stimulation on brain metabolism (18FDG PET) in patient with OCD: Case report
2003
Abstract
The patient (20y.) with a pharmacoresistant form of obsessive-compulsive disorder (OCD) was treated for 3 weeks by the low-frequency rTMS (1 Hz, 20 min., 100% MT). A 32% decrease in the psychopathology (Y-BOCS) was observed during rTMS treatment.
The regional brain metabolism (18FDG PET) decreased in the prefrontal cortex, caudate, and other regions. The case report demonstrates that rTMS should therapeutically interfere with the causal pathophysiologic mechanisms of OCD.