Neuroendocrine or behavioral effects of acute or chronic emotional stress in Wistar Kyoto (WKY) and spontaneously hypertensive (SHR) rats

Abstract

The results of the present study revealed higher pituitary-adrenocortical response to mild stressor of acute handling in SHR than in Wistar Kyoto rats. SHR showed also higher anxiety related behavior than WKY rats when measured by elevated plus-maze test.

These results suggest common pathways for neuroendocrine and behavioral changes in the SHR

Keywords

• Neuroendocrine
• behavioral
• effects
• acute
• chronic
• emotional
• stress
• Wistar
• Kyoto
• WKY
• spontaneously
• hypertensive
• SHR
• rats