Patient with long-lasting history of drug dependency (opiares and merampheramine) was investigated by the use of positron eniis sion tomography ( PET) due to the persistent acoustic hallucinations and paranoid delusions. The psychotic symproms have persisted over 2 years ofthe full abstinence.
Increased metabolism ( uprake) was found in temporo-parietal corteX bilaterally in comparison wirh the controls (SPM). The current knowledge about bram metabolic changes in residual toxic psychoses is limited.
The symmetric increase of metabolism within the temporo-parietal corteX would reflect the finding nosologically specific finding in the hallucinations of toxic origin.