Abstract
Insulin glargine (Lantus) is a modern tool for the treatment of both type 1 and type 2 diabetes mellitus offering 24hours covering of the basal insulin demand, in addition to a more or less stable level. The important part of a correct therapy adjustment is a gradual up titration of the insulin doses aiming to achieve normal glycemia.
One of the recommended methods of patient?s self up titration of glargine (Lantus) is a method of 3 day steps with a gradual efforts to achieve targeted morning fasting glycemia of <= 5,5 mmol/l. The case history presents an example of such a method in a female patient with type 2 diabetes mellitus treated by the intensified insulin regime, in whom so far used human insulins were replaced by their analogues (lispro, glargine)