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The pattern of brain activity in reaction to complex motor stimulation differs in multiple sclerosis and healthy. There is a trend to normalization of this pattern in connection with physiotherapy

Publication at First Faculty of Medicine, Third Faculty of Medicine |
2008

Abstract

On fMRI, the examination 1 shows a statistically significant difference between healthy probands and MS patients in the proportion of activated voxels for the right hand (sequence RL - the movement is carried out by the right hand immediately followed by the left hand) as "navigator hand" (the first one) to "tandem hand" (the second one). After the physiotherapy MS patients did not prove a statistically significant change in the proportion of voxels.

As the examination 2 does not prove any difference between the healthy and MS patients in the proportion of voxels, in this sense we can think of the "recovery to the normal". Nevertheless, the above mentioned conclusions need further verification on the larger sample of probands in the groups.