Double - blind, parallel, randomized study comparing efficacy of 1 Hz repetitive transcranial magnetic stimulation (rTMS) and venlafaxine ER in the treatment of resistant depression: discussion on study protocol

Abstract

The rTMS is noninvasive method of brain stimulation, which is indicated for the treatment of depression in CR. A new, randomized, double-blind study comparing efficacy of 1 Hz stimulation over right dorsolateral prefrontal cortex and venlafaxine ER has started in 2005.

The authors discuss some details of clinical study design reflecting new findings in the treatment of depression

Keywords

• resistant depression
• treatment
• repetitive transcranial magnetic stimulation (rTMS)
• venlafaxine
• dorsolateral prefrontal cortex