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Prediction of therapeutic response in patients suffering from obsessive compulsive disorder resistant to the treatment with psychopharmacs

Publication |
2008

Abstract

The purpose of the present study is to examine the effectiveness of CBT on a sample of non-selected, pharmacoresistant OCD patients and to find the predictors of successful treatment in these conditions. The therapy was conducted in a naturalistic setting and systematic CBT steps were adapted to each patient.

Pharmacological treatment underwent no or minimal changes during the trial period. Outcome measures included the Yale-Brown Obsessive Compulsive Scale, subjective version (S-Y-BOCS), the Clinical Global Impressions-Severity of Illness scale (CGI-S), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Somatoform Dissociation Questionaire (SDQ-20) and Dissociative Experience Scale (DES).